Mcom 15mg Tablets Pharmacokinetics Absorption
Oral/rectal: Well absorbed. Metabolism: Hepatic. Bioavailability: 89%. Half-life elimination: 20 hrs. Time to peak, plasma: 6 hrs. IM: 1.5 hrs. Excretion: Urine. Faeces.
Anticoagulants, lithium, IUDs, methotrexate, cholestyramine, diuretics, cyclosporin, antihypertensives, thrombolytics, other NSAIDs, tacrolimus, antiplatelets, SSRIS, corticosteroids.
Gl perforation, ulceration, bleeding or upset; monitor patient. Muco-cutaneous reactions including pruritus, rash, urticaria, angioedema, photosensitivity, erythema multiforme, Stevens-Johnson syndrome. CNS or cardiovascular effects, blood dyscrasias, transient disturbances in liver tests. Headache, Gl upset, fluid and electrolyte disturbances