Flagyl 400mg Tablets Infection due to anaerobic pathogens. Amoebic dysentery, liver abscess and other forms of amoebic disease. Eradication of E. histolytica from symptomless cyst passers. Acute ulcerative gingivitis. Trichomoniasis. Non-specific vaginitis.
Adults: Infections due to anaerobic pathogens:
ORAL: 400 mg three times daily.
500 mg eight hourly by IV infusion then oral therapy. Invasive intestinal diseases in susceptible subjects: ORAL: 800 mg three times daily for five days: less susceptible subjects: 400 mg three times daily for five to ten days. Hepatic diseases, including amoebic liver abscess and hepatitis and other forms of extra-intestinal amoebic disease: ORAL: 400-800 mg three times daily for five days. Pelvic inflammatory disease: ORAL: 400 mg twice daily for 14 days. Symptomless cyst passers: ORAL: 400-800 mg three times daily for five to ten days. Acute ulcerative gingivitis: ORAL: 400 mg three times daily for three days. Acute oral infections: ORAL: 400 mg every 8 hr for 3-7 days. Leg ulcers and pressure sores: ORAL: 400 mg every 8 hr for 7 days. Trichomoniasis/Non-specific vaginitis: ORAL: 400 mg twice daily for 7 days or 200 mg three times daily for seven days or 800 mg in the morning and 1200 mg at night for two days or 2 gm as a single dose. Treat male partner concurrently. Surgical prophylaxis: ORAL: 400-500 mg 2 hr before surgery; up to 3 further doses of 400-500 mg may be given every 8 hr for high-risk procedures. INJECTION: By IV infusion 500 mg up to 30 minutes before the procedure, further 3 doses of 500 mg every 8 hr may be given for high-risk procedures. Children: Anaerobic infections (usually treated for 7 days and for 10-14 days in Clostridium difficile infection): ORAL: 1-2 mth, 7.5 mg/ kg every 12 hr; 2 mth-12 yr, 7.5 mg/kg, max 400 mg, every 8 hr; 12-18 yr, 400 mg every 8 hr. INJECTION: By IV infusion over 20-30 minutes. Neonate less than 26 wk corrected gestational age, 15 mg/kg as a single loading dose followed after 24 hr by 7.5 mg/kg daily; Neonate 26-34 wk corrected gestational age, 15 mg/kg as a single loading dose followed after 12 hr by 7.5 mg/kg every 12 hr; Neonate over 34 wk corrected gestational age, 15 mg/kg as a single loading dose followed after 8 hr by 7.5 mg/kg every 8 hr; 1-2 mth, 15 mg/kg as a single loading dose followed after 8 hr by 7.5 mg/kg every 8 hr; 2 mth-18 yr, 7.5 mg/kg, max 500 mg, every 8 hr. Pelvic inflammatory disease:.
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