Etipro 20mg Capsules Oesophageal reflux disease, reflux oesophagitis. Long-term management of acid-reflux disease. Duodenal and benign gastric ulcers including those complicating NSAID therapy. Duodenal ulcers associated with H. pylori. Zollinger-Ellison syndrome. Prophylaxis of acid aspiration during general anaesthesia.
ORAL: Duodenal ulcer: 20 mg once daily for 4 wk. Severe cases, increase to 40 mg once daily. Prevention of relapse, 20 mg once daily, dose may range between 10 mg to 40 mg daily. Gastric ulcer: 20 mg once daily for 8 wk. Severe cases, increase to 40 mg once daily. Prevention of relapse, 20 mg once daily, increased to 40 mg once daily if necessary. Acid-reflux disease: Long-term management, 10 mg once daily, increasing to 20 mg once daily if symptoms return. GERD: 20 mg once daily for 4 wk, extend for a further 4-8 wk if not fully healed. Refractory cases, 40 mg once daily x 8 wk, maintenance 20 mg once daily. Acid related dyspepsia: 10-20 mg once daily for 2-4 wk according to response. NSAID associated duodenal or gastric ulcer or erosions: 20 mg once daily for 4 wk, may be continued for further 4 wk if necessary. Prophylaxis for history of NSAID duodenal or gastric ulcer or erosions or dyspeptic symptoms: 20 mg once daily. Zollinger-Ellison syndrome: 60 mg once daily, adjusted to response. Usual maintenance, 20-120 mg daily. Doses above 80 mg daily, give in two divided doses. Reflux oesophagitis: 20 mg once daily for 4 wk, extend for a further 4-8 wk if not fully healed. Refractory cases, 40 mg once daily. DU with H. pylori: 40 mg once daily for 2 wk with antibacterials as recommended. Acid aspiration: 40 mg in the evening of day before surgery, then 40 mg 1-4 hrs prior to surgery. Adults: INJECTION: IV infusion over 20-30 min or IV injection over 5 min. Prophylaxis of acid aspiration: 40mg completed 1 hr before surgery. Treatment and prevention of benign gastric ulcer, duodenal ulcer, NSAID-associated ulcer & gastro-oesophageal reflux: 40mg once daily until oral administration possible. Zollinger-Ellison syndrome: Initially 60 mg once daily if above 60 mg/ day the dose is divided in 2 doses. Major peptic ulcer bleeding (following endoscopic treatment): Initial IV inf of 80 mg over 40-60 min, then by continuous IV inf, 8 mg/hr for 72 hrs, then change to oral therapy.
Children: Capsules/tablets not recommended for children except for severe ulcerating reflux oesophagitis in children over 1 yr.