Esomega 20mg Capsules

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Esomeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough.

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Description

Indications

Erosive reflux oesophagitis, prevention of relapse of oesophagitis, symptomatic treatment of GERD. Zollinger-Ellison syndrome, severe peptic ulcer bleeding (following endoscopic treatment). In combination with antibiotics for the eradication of H. pylori, healing of H. pylori-associated duodenal ulcer and prevention of relapse of H. pylori-associated peptic ulcers. Treatment and prevention of NSAID-associated peptic ulceration.

Dosage

ORAL:

Adults: Erosive oesophagitis: 40 mg once daily for 4-8 wk. Prevention of relapse, 20 mg once daily. GERD without oesophagitis: 20 mg once daily for 4 wk. Maintenance, 20 mg once daily as required. Zollinger-Ellison syndrome: Initially 40 mg two times daily, can be altered according to response. Usual dose: 80-160 mg daily, doses over 80 mg must be given in two divided doses. Triple therapy vs H. pylori: 20 mg twice daily with amoxicillin 1 gm twice daily and clarithromycin 500 mg twice daily for 7 days. NSAID ulceration: 20 mg once daily for 4-8 wk, Prevention, 20 mg once daily. Children: Not recommended.

INJECTION:

Adults: Reflux oesophagitis: 40 mg once daily given as IV inj over a period of at least 3 min or as IV inf over a period of 10-30 min. Symptomatic treatment of reflux oesophagitis: 20 mg once daily, half of the reconstituted solution be given as IV inj over a period of at least 3 min or as IV inf over a period of 10-30 min. Healing of gastric ulcer associated with NSAID therapy & duodenal ulcers associated with NSAID therapy: 20 mg once daily to be given over atleast 3 min. Treatment duration is usually short and shift to oral dose as soon as possible. Severe peptic ulcer bleeding (following endoscopic treatment: Initial IV infusion of 80 mg over 30 min, then by continuous IV infusion 8 mg/hr for 72 hr, then by mouth 40 mg once daily for 4 wk. Children: By IV injection or by IV infusion. GERD in the presence of erosive reflux oesophagitis: 1-12 yr, body weight under 20 kg, 10 mg once daily; body weight over 20 kg, 10-20 mg once daily; 12-18 yr, 40 mg once daily. GERD in the absence of erosive reflux oesophagitis: 1-12 yr, 10 mg once daily; 12-18 yr, 20 mg once daily.

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