Indications
Primolut N 5mg is primarily indicated in conditions like Contraception, Dysfunctional uterine bleeding, Dysmenorrhoea, Endometriosis, Menstruation disorders, Postponement of menstruation, Premenstrual tension, and can also be given in adjunctive therapy as an alternative drug of choice in Premenstrual syndrome.
Contraindication
Primolut N 5mg is contraindicated in conditions like Acute renal failure,Epilepsy,Breast cancer, Cardiovascular disease, Hepatitis, Liver carcinoma,Amenorrhoea, Herpes gestations, Skin diseases,Bronchial asthma, Hypersensitivity to the drug.
Side Effects
The severe or irreversible adverse effects of Primolut N 5mg, which give rise to further complications include Hepatitis, Cataract, Cholestatic jaundice, Optic neuritis, Hyperglycemia, Hypertension, Mental disturbances, Retinal thrombosis, Uterine myomata, Decreased libido, Vaginitis, Galactorrhea, Breakthrough bleeding, Leukorrhea, Thromboembolism.Primolut N 5mg produces potentially life-threatening effects which include Reduced HDL levels. which are responsible for the discontinuation of Primolut N 5mg therapy.The signs and symptoms that are produced after the acute overdosage of Primolut N 5mg include Nausea, Thromboembolism, Jaundice. The symptomatic adverse reactions produced by Primolut N 5mg are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Fatigue, Anorexia, Anxiety, Abdominal pain, Rashes, Weight LossX, Depression, Weight gain, Elevation of liver enzymes, Nausea and vomiting, Edema, Acne, Hirsutism, Breast discomfort, Intermenstrual bleeding or spotting, Menstrual irregularity, Bloating, Exacerbation of epilepsy, Exacerbation of migraine, Cervicitis.
Warnings
Primolut N 5mg should be used with caution in patients with medical history, including any allergies (especially drug allergies), abnormal vaginal bleeding, liver, kidney or heart disease, cancer of the breast or genitals, missed abortion, blood clots, seizures, migraine, asthma, depression or diabetes. Limit alcohol, as this may increase side effects of this drug. It is not recommended to take it in early pregnancy. Primolut N 5mg Enanthate should be used with caution in patients with cardiovascular or renal impairment, diabetes mellitus, asthma, epilepsy, and migraine, or other conditions which may be aggravated by fluid retention. They should also be used with care in persons with a history of depression. High doses should be used with caution in patients susceptible to thromboembolism. It should not be given to the patients with undiagnosed vaginal bleeding, nor to those with a history or current high risk of arterial disease and should generally be avoided in hepatic impairment, especially if severe.
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