Indications
Meliane Tablets is primarily indicated in conditions like Breast cancer, Breast cancer (unlicensed indication), Dysfunctional uterine bleeding, Gonadal dysgenesis, Heriditary haemorrhagic telangiectasia, Hormone replacement for menopausal symptoms, Hormone replacement therapy, Menopausal Symptoms, Oestrogen deficiency, Osteoporosis prophylaxis, Pre-ovulatory mucus, Prostatic cancer, and can also be given in adjunctive therapy as an alternative drug of choice in Acne, Contraception, Endometriosis, Hirsutism, Menstruation disorders.
Contraindication
Meliane Tablets is contraindicated in conditions like Thromboembolism, Genital bleeding,Jaundice, Thrombophlebitis,Cerebrovas cular disease, Hepatic carcinoma,Coronary artery disease, Estrogen-dependent cancer, Untreated endometriosis.
Side Effects
The severe or irreversible adverse effects of Meliane Tablets, which give rise to further complications include Impotence, Loss of libido, Gyn ac om astia, Chloasma, MI.Meliane Tablets produces potentially life-threatening effects which include Pulmon ary embolism, Hypertension, Venous thromboembolism, Endometrial carcinoma, Endometrial hyperplasia, Cerebral thrombosis, Gall bladder disease, Liver tumors, Breast carcinoma, Venous thromboembolism, Coronary thrombosis, which are responsible for the discontinuation of Meliane Tablets therapy. The signs and symptoms that are produced after the acute overdos age of Meliane Tablets include Nausea, vomiting, Coronary thrombosis, Uterine withdrawal bleeding. The symptom atic adverse reactions produced by Meliane Tablets are more or less tolerable and if they become severe, they can be treated symptom atically, these include Dizziness, Nausea, vomiting, Weight gain, Fluid retention, Intermenstrual bleeding or spotting, Chloasma, Cholestatic Jaundice, Vaginal candidiasis, dizziness.
Warnings
High doses of Meliane Tablets used in treatment of malignant disease should be used with caution in patients with cerebrovascular disorder, coronary artery disease or venous thromboembolism. It should be used with caution in children, because premature closure of epiphysis may occur resulting in inhibited linear growth and small stature.
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