One-Alpha Capsules 0.5mcg is primarily indicated in conditions like Neonatal hypocalcemia, Oncogenic hypophosphatemic osteomalacia, Osteomalacia in malabsorption syndrome, Osteoporosis, Parathyroid bone disease, Renal osteodystrophy, Renal tubular osteomalacia, Rickets in premature infants, Sporadic hypophosphatemic osteomalacia, Uremic osteodystrophy, Vitamin D therapy in patients with severe renal impairment, Vitamin D-dependent rickets, X-linked hypophosphataemic osteomalacia, and can also be given in adjunctive therapy as an alternative drug of choice in Psoriasis
One-Alpha Capsules 0.5mcg is contraindicated in conditions like Hypercalcaemia.
The severe or irreversible adverse effects of One-Alpha Capsules 0.5mcg, which give rise to further complications include Hypercalciuria, Urinary calcium stone formation, Hypercalcemia, CNS depression.One-Alpha Capsules 0.5mcg produces potentially life-threatening effects which include Coma. which are responsible for the discontinuation of One-Alpha Capsules 0.5mcg therapy.The signs and symptoms that are produced after the acute overdosage of One-Alpha Capsules 0.5mcg include Nausea, Vomiting, Diarrhea, Polyuria, Sweating, Headache, Anorexia, Vertigo, Thirst.
Vitamin D should not be administered to patients with hypercalcaemia. Use with extreme caution in children, because they may have increase sensitivity to its effects and should be used with care in patients with renal impairment or calculi or heart disease. Plasma phosphate level should be controlled during vitamin D therapy. Use with caution during pregnancy