Metodine Tablets DF is primarily indicated in conditions like Acute dental infections, Acute ulcerative gingivitis, Amoebiasis, Anaerobic bacterial infection, Anaerobic infections, Dysentery, Giardiasis, Lung cancer and pancreatic cancer, Pelvic inflammatory disease, Protozoa infection, Schizophrenia and other psychoses, Surgical prophylaxis, Treatment of locally advanced or metastatic pancreatic cancer, Trichomoniasis, Urogenital trichomoniasis, and can also be given in adjunctive therapy as an alternative drug of choice in Amoebic liver abscess, Bacterial vaginosis, Cancer, Clostridium difficile colitis, Crohn’s disease, Dental infections, Helicobacter pylori infection.
Metodine Tablets DF is contraindicated in conditions like Alcohol dependence,Blood dyscrasias, Neurosis, Hypersensitivity, Liver damage, Seizures.
The severe or irreversible adverse effects of Metodine Tablets DF, which give rise to further complications include Encephalopathy, Convulsions, Ataxia, Peripheral neuropathy, Neutropenia, Seizures, Depression, Headache, Dysarthria, Aseptic meningitis. The signs and symptoms that are produced after the acute overdosage of Metodine Tablets DF include Disorientation. The symptomatic adverse reactions produced by Metodine Tablets DF are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Vertigo, Headache, Anorexia, Diarrhea, Palpitation, Insomnia, Dry mouth, Maculopapular rash, Rashes, Stomatitis, Urticaria, Pruritus, Dysuria, Gl upset, Flushing, Phlebitis, Nausea and vomiting, Gynecomastia, Chest pain, Metallic taste, Paresthesias, Acute pancreatitis, Darkening of urine, Dry mouth, dizziness, Thrush, Weakness.
Metodine Tablets DF should be used with caution in patients with any allergy. Avoid use during pregnancy or lactation. Avoid alcoholic beverages while taking this medication as severe stomach upset, nausea, vomiting, headache and flushing can occur.