Krotam is analgesic and antipyretic agent. Krotam is the active metabolite of phenacetin, responsible for its analgesic effect. Krotam is a weak prostaglandin inhibitor in peripheral tissues and possesses no significant antinflammatory effects. Krotam is one of the most important drug used for the treatment of mild to moderate pain when an antinfalmmatory effect is not necessary, Krotam is preferred over aspirin as an analgesic/antipyretic for patients in whom aspirin is contraindicated, such as those who have a history of gastric ulcer or a coagulation disorder
Krotam is primarily indicated in conditions like Ear pain, Fever, Headache, Malaise, Migraine, Mild to moderate pain, Pain, Post-vaccinereaction, Short-bowel syndrome, Tobacco amblyopia and leber’s optic atrophy. Toothache.
Krotam is contraindicated in conditions like Hypersensitivity
The severe or irreversible adverse effects of Krotam, which give rise to further complications include Bronchospasm.Krotam produces potentially life-threatening effects which include Blood dyscrasias, Centribular Necrosis, Liver damage which are responsible for the discontinuation of Krotam therapy. The signs and symptoms that are produced after the acute overdosage of Krotam include hypoglycemic coma, Hepatic necrosis, Liver failure, renal tubular necrosis. The symptomatic adverse reactions produced by Krotam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin rashes, Gladverse effects
if sensitivity reaction occurs, discontinue use of Krotam. If pain persist more than 10 days and arthritic and rheumatic condition affecting children, immediately consult physician. If patient have been diagnosed with liver or kidney impairment, seek medical advice before taking medication. If symptoms persists consult doctor
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies