Famopsin Pregnancy: No evidence of risk in humans. Lactation: Contraindicated or not recommended. Precautions: Impaired renal function, gastric carcinoma. Exclude malignancy before treatment. Monitor blood count and liver function during long-term use.
Indications Duodenal and benign gastric ulcers. Prevention of relapse of duodenal ulceration. Zollinger-Ellison syndrome. Prevention and treatment of gastro-oesophageal reflux disease. Dosage Adults: Benign gastric and duodenal ulcer: 40 mg once daily at night for 4-8 wk. Prophylaxis of duodenal ulcer relapse: 20 mg once daily at night. Zollinger-Ellison syndrome: Initially 20 mg every 6 hr, adjust as necessary; max 800 mg daily. Gastro-oesophageal reflux disease: 20 mg twice daily for 6-12 wk; if also erosion or ulceration, 40 mg twice daily for 6-12 wk. Prophylaxis 20 mg twice daily. Heartburn, indigestion, sour stomach: 10-20 mg every 12 hr, the dosage may be taken 15-60 min before eating foods known to cause heartburn. Max 40 mg/day. Children: Peptic ulcer: 1-16 yr: 0.5 mg/kg/day