Irbesartan is an antihypertensive agent, belongs to angiotensin Il receptor antagonists The actions, uses and adverse effects are similar to those of losartan. Irbesartan is used either alone or in combination with other antihypertensive agents for the management of hypertension and other cardiovascular disorders
Irbesartan is primarily indicated in conditions like Hypertension, and can also be given in adjunctive therapy as an alternative drug of choice in Diabetic nephropathy, Heart failure, Renal disease in hypertensive type il diabetes mellitus
Irbesartan is contraindicated in conditions like Pregnancy, Breast feeding
The severe or irreversible adverse effects of Irbesartan, which give rise to further complications include Hyperkalemia, Impaired renal function, Myelgia. The symptomatic adverse reactions produced by Irbesartan are more or less tolerable and if they become severe, they can be treated symptomatically, these include Duziness, Headache, Fatigue, Tachycardia, Abdominal pain, Rashes, Confusion, Pharyngitis, Hypotension, Nausea and vomiting, Edema, Rhinitis, Chest pain, Angioedema, UTI, Confusion, dizziness.
Use with caution in renal artery stenosis, aortic or mitral valve stenosis and in obstructive hypertrophic cardiomyopathy. Monitor plasma-potassium concentration particularly in elderly and in patients with renal impairment; lower initial doses may be appropriate in these patients.
High Risk Groups
Drug should not be given to Pregnant Mothers. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies